Symptom recurrence after resection was found in 6 of 31 at a mean of 13 months postoperatively and was associated with death from disease ( P <0.05) or presence of pain preoperatively.Ī pesar de que los seudoquistes constituyen la mayor parte de las lesiones quísticas pancreáticas, es importante realizar un correcto diagnóstico diferencial con las verdaderas neoplasias quísticas, debido fundamentalmente a su potencial maligno. Three-year actuarial survival was 82% (all) and 36% (malignant). In 31 resected patients after a follow-up of 37 months (1 to 103) death had occurred in 6 of 13 malignant cases and 0 of 18 with benign disease. Jaundice or presence in both MPD and SBD approached a significant association with malignancy but not abdominal pain, weight loss, diabetes, preoperative serum elevations of amylase, SGOT, CA-19-9, or CEA diffuse MPD dilation, gland region, gross mucus in ducts or filling defects, cytology, calcifications, or a pancreatic mass. Factors significantly associated ( P <0.05 Fisher exact test) with malignancy were history of alcohol abuse or death from disease. Operations were pancreatectomy in 31 (Whipple n = 15, total n = 5, distal n = 10, local n = 1), bypass only (n = 1), and no operation (n = 1). Clinical presentation was epigastric pain (82%), pancreatitis (56%), weight loss (36%), diabetes (27%), and jaundice (9%). Our cases were older (65 years) and presented with disease centered mainly in the head of the gland.
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